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Co-administration of Favipiravir and the Remdesivir Metabolite GS-441524 Effectively Reduces SARS-CoV-2 Replication in the Lungs of the Syrian Hamster Model

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread worldwide since December 2019, causing coronavirus disease 2019 (COVID-19). Although vaccines for this virus have been developed rapidly, repurposing drugs approved to treat other diseases remains an invaluable treatment strateg...

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Detalles Bibliográficos
Autores principales: Chiba, Shiho, Kiso, Maki, Nakajima, Noriko, Iida, Shun, Maemura, Tadashi, Kuroda, Makoto, Sato, Yuko, Ito, Mutsumi, Okuda, Moe, Yamada, Shinya, Iwatsuki-Horimoto, Kiyoko, Watanabe, Tokiko, Imai, Masaki, Armbrust, Tammy, Baric, Ralph S., Halfmann, Peter J., Suzuki, Tadaki, Kawaoka, Yoshihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8805032/
https://www.ncbi.nlm.nih.gov/pubmed/35100870
http://dx.doi.org/10.1128/mbio.03044-21