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Mapping Critical Residues in ATG11’s Coiled-Coil 2 Domain that Block Multiple Interactions and Disrupt Selective Autophagy

Selective autophagy is a conserved subcellular process that maintains the health of eukaryotic cells by targeting damaged or toxic cytoplasmic components to the vacuole/lysosome for degradation. A key player in the initiation of selective autophagy in S. Cerevisiae (baker’s yeast) is a large adapter...

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Detalles Bibliográficos
Autores principales: Meyer, Mitchell D., Winzeler, Jasmine, Taylor, Sophia M., Kilgore, Alex, Edicha, Kimberly, Chitwood, Chase, Spearin, Zachary, Silvia, S. K. Nadia Rahman, Chakraborty, Ronith, Smith, Jesse E., Kennedy, Bridget, Zois, Carson, Cawthon, Hayley, Gilruth, Mukiri, Backues, Steven K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8805157/
https://www.ncbi.nlm.nih.gov/pubmed/35118068
http://dx.doi.org/10.3389/fcell.2021.775364