Hippocampal Disinhibition Reduces Contextual and Elemental Fear Conditioning While Sparing the Acquisition of Latent Inhibition

Hippocampal neural disinhibition, i.e., reduced GABAergic inhibition, is a key feature of schizophrenia pathophysiology. The hippocampus is an important part of the neural circuitry that controls fear conditioning and can also modulate prefrontal and striatal mechanisms, including dopamine signaling...

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Detalles Bibliográficos
Autores principales: Williams, Stuart A., Gwilt, Miriam, Hock, Rebecca, Taylor, Charlotte, Loayza, Joanna, Stevenson, Carl W., Cassaday, Helen J., Bast, Tobias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2022
Materias:
Research Article: New Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8805190/
https://www.ncbi.nlm.nih.gov/pubmed/34980662
http://dx.doi.org/10.1523/ENEURO.0270-21.2021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8805190/
https://www.ncbi.nlm.nih.gov/pubmed/34980662
http://dx.doi.org/10.1523/ENEURO.0270-21.2021

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