Crystal structures of the ligand-binding domain of human peroxisome proliferator-activated receptor δ in complexes with phenylpropanoic acid derivatives and a pyridine carboxylic acid derivative

Peroxisome proliferator-activated receptor δ (PPARδ) is a member of the nuclear receptor family and regulates glucose and lipid homeostasis in a ligand-dependent manner. Numerous phenylpropanoic acid derivatives targeting three PPAR subtypes (PPARα, PPARγ and PPARδ) have been developed towards the t...

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Detalles Bibliográficos
Autores principales: Oyama, Takuji, Takiguchi, Kazuki, Miyachi, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2022
Materias:
Research Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8805212/
https://www.ncbi.nlm.nih.gov/pubmed/35102897
http://dx.doi.org/10.1107/S2053230X22000449

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8805212/
https://www.ncbi.nlm.nih.gov/pubmed/35102897
http://dx.doi.org/10.1107/S2053230X22000449

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