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Detecting gene–gene interactions from GWAS using diffusion kernel principal components

Genes and gene products do not function in isolation but as components of complex networks of macromolecules through physical or biochemical interactions. Dependencies of gene mutations on genetic background (i.e., epistasis) are believed to play a role in understanding molecular underpinnings of co...

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Detalles Bibliográficos
Autores principales: Walakira, Andrew, Ocira, Junior, Duroux, Diane, Fouladi, Ramouna, Moškon, Miha, Rozman, Damjana, Van Steen, Kristel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8805268/
https://www.ncbi.nlm.nih.gov/pubmed/35105309
http://dx.doi.org/10.1186/s12859-022-04580-7