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Detecting gene–gene interactions from GWAS using diffusion kernel principal components
Genes and gene products do not function in isolation but as components of complex networks of macromolecules through physical or biochemical interactions. Dependencies of gene mutations on genetic background (i.e., epistasis) are believed to play a role in understanding molecular underpinnings of co...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8805268/ https://www.ncbi.nlm.nih.gov/pubmed/35105309 http://dx.doi.org/10.1186/s12859-022-04580-7 |