Association between single moderate to severe traumatic brain injury and long-term tauopathy in humans and preclinical animal models: a systematic narrative review of the literature

BACKGROUND: The initiation, anatomic pattern, and extent of tau spread in traumatic brain injury (TBI), and the mechanism by which TBI leads to long-term tau pathology, remain controversial. Some studies suggest that moderate to severe TBI is sufficient to promote tau pathology; however, others sugg...

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Detalles Bibliográficos
Autores principales: Walker, Ariel, Chapin, Ben, Abisambra, Jose, DeKosky, Steven T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8805270/
https://www.ncbi.nlm.nih.gov/pubmed/35101132
http://dx.doi.org/10.1186/s40478-022-01311-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8805270/
https://www.ncbi.nlm.nih.gov/pubmed/35101132
http://dx.doi.org/10.1186/s40478-022-01311-0

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