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Real space in cryo-EM: the future is local

Cryo-EM images have extremely low signal-to-noise levels because biological macromolecules are highly radiation-sensitive, requiring low-dose imaging, and because the molecules are poor in contrast. Confident recovery of the signal requires the averaging of many images, the iterative optimization of...

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Detalles Bibliográficos
Autores principales: Palmer, Colin M., Aylett, Christopher H. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8805303/
https://www.ncbi.nlm.nih.gov/pubmed/35102879
http://dx.doi.org/10.1107/S2059798321012286