Rapamycin, Acarbose and 17α-estradiol share common mechanisms regulating the MAPK pathways involved in intracellular signaling and inflammation

BACKGROUND: Rapamycin (Rapa), acarbose (ACA), and 17α-estradiol (17aE2, males only) have health benefits that increase lifespan of mice. Little is known about how these three agents alter the network of pathways downstream of insulin/IGF1 signals as well as inflammatory/stress responses. RESULTS: AC...

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Detalles Bibliográficos
Autores principales: Wink, Lily, Miller, Richard A., Garcia, Gonzalo G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8805398/
https://www.ncbi.nlm.nih.gov/pubmed/35105357
http://dx.doi.org/10.1186/s12979-022-00264-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8805398/
https://www.ncbi.nlm.nih.gov/pubmed/35105357
http://dx.doi.org/10.1186/s12979-022-00264-1

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