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Sparser and Less Efficient Hippocampal-Prefrontal Projections account for Developmental Network Dysfunction in a Model of Psychiatric Risk Mediated by Gene-Environment Interaction

Precise information flow from the hippocampus (HP) to prefrontal cortex (PFC) emerges during early development and accounts for cognitive processing throughout life. On flip side, this flow is selectively impaired in mental illness. In mouse models of psychiatric risk mediated by gene-environment in...

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Detalles Bibliográficos
Autores principales: Song, Lingzhen, Xu, Xiaxia, Putthoff, Peggy, Fleck, David, Spehr, Marc, Hanganu-Opatz, Ileana L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8805616/
https://www.ncbi.nlm.nih.gov/pubmed/34844990
http://dx.doi.org/10.1523/JNEUROSCI.1203-21.2021