Mendelian randomization analyses implicate biogenesis of translation machinery in human aging

Reduced provision of protein translation machinery promotes healthy aging in a number of animal models. In humans, however, inborn impairments in translation machinery are a known cause of several developmental disorders, collectively termed ribosomopathies. Here, we use casual inference approaches...

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Detalles Bibliográficos
Autores principales: Javidnia, Sara, Cranwell, Stephen, Mueller, Stefanie H., Selman, Colin, Tullet, Jennifer M.A., Kuchenbaecker, Karoline, Alic, Nazif
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8805714/
https://www.ncbi.nlm.nih.gov/pubmed/35078808
http://dx.doi.org/10.1101/gr.275636.121

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8805714/
https://www.ncbi.nlm.nih.gov/pubmed/35078808
http://dx.doi.org/10.1101/gr.275636.121

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