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Characterization of transcript enrichment and detection bias in single-nucleus RNA-seq for mapping of distinct human adipocyte lineages

Single-cell RNA sequencing (scRNA-seq) enables molecular characterization of complex biological tissues at high resolution. The requirement of single-cell extraction, however, makes it challenging for profiling tissues such as adipose tissue, for which collection of intact single adipocytes is compl...

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Detalles Bibliográficos
Autores principales: Gupta, Anushka, Shamsi, Farnaz, Altemose, Nicolas, Dorlhiac, Gabriel F., Cypess, Aaron M., White, Andrew P., Yosef, Nir, Patti, Mary Elizabeth, Tseng, Yu-Hua, Streets, Aaron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8805720/
https://www.ncbi.nlm.nih.gov/pubmed/35042723
http://dx.doi.org/10.1101/gr.275509.121