Saxagliptin enhances osteogenic differentiation in MC3T3-E1 cells, dependent on the activation of AMP-activated protein kinase α (AMPKα)/runt-related transcription factor-2 (Runx-2)

Osteoporosis is a metabolic bone disease commonly observed in the elderly, and its pathogenesis is associated with declined osteogenic differentiation. Osteogenic differentiation could be facilitated by the activation of the AMP-activated protein kinase (AMPK) pathway. Saxagliptin, an anti-diabetic...

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Detalles Bibliográficos
Autores principales: Wang, Qiang, Xie, Xiaoxing, Zhang, Dehua, Mao, Feng, Wang, Shaobo, Liao, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8805826/
https://www.ncbi.nlm.nih.gov/pubmed/35258398
http://dx.doi.org/10.1080/21655979.2021.2008667

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8805826/
https://www.ncbi.nlm.nih.gov/pubmed/35258398
http://dx.doi.org/10.1080/21655979.2021.2008667

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