Cargando…

Long non-coding RNA HCG11 enhances osteosarcoma phenotypes by sponging miR-1245b-5p that directly inhibits plakophilin 2

Long non-coding RNA (lncRNA) HCG11 can regulate various cancers through the ceRNA network. However, its role in osteosarcoma (OS) remains unknown. The HOS and Saos-2 cell lines were used for in vitro analyses. HCG11 and plakophilin 2 (PKP2) silencers, a miR-1245b-5p mimic, and a miR-1245b-5p inhibit...

Descripción completa

Detalles Bibliográficos
Autores principales: Yan, Hao, Zhou, Yong, Chen, Zhujiang, Yan, Xiaokang, Zhu, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8805843/
https://www.ncbi.nlm.nih.gov/pubmed/34949159
http://dx.doi.org/10.1080/21655979.2021.2010367