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The protective effects of dezocine on interleukin-1β-induced inflammation, oxidative stress and apoptosis of human nucleus pulposus cells and the possible mechanisms

Intervertebral disc degeneration (IDD) is a natural problem linked to the inflammation. We aimed to investigate the role of dezocine (DEZ) in the development of IDD. Human nucleus pulposus cells (HNPCs) induced by interleukin (IL)-1β was used as a cellular model of IDD. After treatment with DEZ, HNP...

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Detalles Bibliográficos
Autores principales: Zhu, Fang, Duan, Wei, Zhong, Chao, Ji, Bing, Liu, Xinjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8805889/
https://www.ncbi.nlm.nih.gov/pubmed/34974796
http://dx.doi.org/10.1080/21655979.2021.2017700