Cargando…

Upregulation of miR-140-5p uncouples mitochondria by targeting Bcl-xL in vascular smooth muscle cells in angiotensin II-induced hypertension

Angiotensin II–induced vascular smooth muscle cell (VSMC) remodeling and dysfunction is a major contributor to the development of hypertension. In spite of the low content of mitochondria and their low contribution to bioenergetics in VSMCs, recent studies have suggested that mitochondria play an im...

Descripción completa

Detalles Bibliográficos
Autores principales: Tuo, Buxiong, Xu, Jie, Zhang, Wenqiang, Li, Xiaomiao, Peng, Lijing, Zou, Qian, Deng, Ying, Lei, Junning, Li, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8805896/
https://www.ncbi.nlm.nih.gov/pubmed/35258391
http://dx.doi.org/10.1080/21655979.2021.2017696