Upregulation of serum and glucocorticoid-regulated kinase 1 (SGK1) ameliorates doxorubicin-induced cardiotoxic injury, apoptosis, inflammation and oxidative stress by suppressing glucose regulated protein 78 (GRP78)-mediated endoplasmic reticulum stress

The clinical application of doxorubicin (Dox) in tumor chemotherapy is limited by time-dependent and dose-dependent cardiotoxicity. Hence, there is an urgent need to elucidate doxorubicin cardiotoxicity and to solve the difficult problem in clinical application. It has been verified that serum and g...

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Detalles Bibliográficos
Autores principales: Wang, Feng, Han, Lili
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8805919/
https://www.ncbi.nlm.nih.gov/pubmed/34898378
http://dx.doi.org/10.1080/21655979.2021.2013109

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8805919/
https://www.ncbi.nlm.nih.gov/pubmed/34898378
http://dx.doi.org/10.1080/21655979.2021.2013109

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