Induction of lncRNA NORAD accounts for hypoxia-induced chemoresistance and vasculogenic mimicry in colorectal cancer by sponging the miR-495-3p/ hypoxia-inducible factor-1α (HIF-1α)

Hypoxic microenvironment represents the hallmark of solid tumors including colorectal cancer (CRC) and facilitates angiogenesis and chemoresistance, leading to poor prognosis. lncRNA NORAD acts as an oncogenic gene to orchestrate cancer progression by regulating cell proliferation and migration. Not...

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Detalles Bibliográficos
Autores principales: Zhang, Lei, Wu, Huili, Zhang, Yong, Xiao, Xingguo, Chu, Feifei, Zhang, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8805945/
https://www.ncbi.nlm.nih.gov/pubmed/34969360
http://dx.doi.org/10.1080/21655979.2021.2015530

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8805945/
https://www.ncbi.nlm.nih.gov/pubmed/34969360
http://dx.doi.org/10.1080/21655979.2021.2015530

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