Immunopeptidomic analysis of influenza A virus infected human tissues identifies internal proteins as a rich source of HLA ligands

CD8+ and CD4+ T cells provide cell-mediated cross-protection against multiple influenza strains by recognising epitopes bound as peptides to human leukocyte antigen (HLA) class I and -II molecules respectively. Two challenges in identifying the immunodominant epitopes needed to generate a universal...

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Detalles Bibliográficos
Autores principales: Nicholas, Ben, Bailey, Alistair, Staples, Karl J., Wilkinson, Tom, Elliott, Tim, Skipp, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8806059/
https://www.ncbi.nlm.nih.gov/pubmed/35051231
http://dx.doi.org/10.1371/journal.ppat.1009894

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8806059/
https://www.ncbi.nlm.nih.gov/pubmed/35051231
http://dx.doi.org/10.1371/journal.ppat.1009894

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