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Metformin Alleviates Neuroinflammation Following Intracerebral Hemorrhage in Mice by Regulating Microglia/Macrophage Phenotype in a Gut Microbiota-Dependent Manner

The gut microbiota plays a key role in regulating intracerebral hemorrhage (ICH)-induced neuroinflammation. The anti-neuroinflammatory effects of metformin (Met) have been reported in many central nervous system (CNS) diseases. However, whether Met regulates neuroinflammation through the gut microbi...

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Detalles Bibliográficos
Autores principales: Yu, Xiaobo, Fu, Xiongjie, Wu, Xinyan, Tang, Wenwen, Xu, Lei, Hu, Libin, Xu, Chaoran, Zhou, Hang, Zhou, Guoyang, Li, Jianru, Cao, Shenglong, Liu, Jiang, Yan, Feng, Wang, Lin, Liu, Fuyi, Chen, Gao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8806158/
https://www.ncbi.nlm.nih.gov/pubmed/35115909
http://dx.doi.org/10.3389/fncel.2021.789471