Machine learning reveals bilateral distribution of somatic L1 insertions in human neurons and glia

Retrotransposons can cause somatic genome variation in the human nervous system, which is hypothesized to have relevance to brain development and neuropsychiatric disease. However, the detection of individual somatic mobile element insertion (MEIs) presents a difficult signal-to-noise problem. Using...

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Detalles Bibliográficos
Autores principales: Zhu, Xiaowei, Zhou, Bo, Pattni, Reenal, Gleason, Kelly, Tan, Chunfeng, Kalinowski, Agnieszka, Sloan, Steven, Fiston-Lavier, Anna-Sophie, Mariani, Jessica, Petrov, Dmitri, Barres, Ben A., Duncan, Laramie, Abyzov, Alexej, Vogel, Hannes, Moran, John V., Vaccarino, Flora M., Tamminga, Carol A., Levinson, Douglas F., Urban, Alexander E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8806165/
https://www.ncbi.nlm.nih.gov/pubmed/33432196
http://dx.doi.org/10.1038/s41593-020-00767-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8806165/
https://www.ncbi.nlm.nih.gov/pubmed/33432196
http://dx.doi.org/10.1038/s41593-020-00767-4

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