Developmental single-cell transcriptomics of hypothalamic POMC neurons reveal the genetic trajectories of multiple neuropeptidergic phenotypes

Proopiomelanocortin (POMC) neurons of the hypothalamic arcuate nucleus are essential to regulate food intake and energy balance. However, the ontogenetic transcriptional programs that specify the identity and functioning of these neurons are poorly understood. Here, we use single-cell RNA-sequencing...

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Detalles Bibliográficos
Autores principales: Yu, Hui, Rubinstein, Marcelo, Low, Malcolm J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8806186/
https://www.ncbi.nlm.nih.gov/pubmed/35044906
http://dx.doi.org/10.7554/eLife.72883

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8806186/
https://www.ncbi.nlm.nih.gov/pubmed/35044906
http://dx.doi.org/10.7554/eLife.72883

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