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Sensitizing Staphylococcus aureus to antibacterial agents by decoding and blocking the lipid flippase MprF

The pandemic of antibiotic resistance represents a major human health threat demanding new antimicrobial strategies. Multiple peptide resistance factor (MprF) is the synthase and flippase of the phospholipid lysyl-phosphatidylglycerol that increases virulence and resistance of methicillin-resistant...

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Detalles Bibliográficos
Autores principales: Slavetinsky, Christoph J, Hauser, Janna N, Gekeler, Cordula, Slavetinsky, Jessica, Geyer, André, Kraus, Alexandra, Heilingbrunner, Doris, Wagner, Samuel, Tesar, Michael, Krismer, Bernhard, Kuhn, Sebastian, Ernst, Christoph M, Peschel, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8806190/
https://www.ncbi.nlm.nih.gov/pubmed/35044295
http://dx.doi.org/10.7554/eLife.66376