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Sensitizing Staphylococcus aureus to antibacterial agents by decoding and blocking the lipid flippase MprF
The pandemic of antibiotic resistance represents a major human health threat demanding new antimicrobial strategies. Multiple peptide resistance factor (MprF) is the synthase and flippase of the phospholipid lysyl-phosphatidylglycerol that increases virulence and resistance of methicillin-resistant...
Autores principales: | Slavetinsky, Christoph J, Hauser, Janna N, Gekeler, Cordula, Slavetinsky, Jessica, Geyer, André, Kraus, Alexandra, Heilingbrunner, Doris, Wagner, Samuel, Tesar, Michael, Krismer, Bernhard, Kuhn, Sebastian, Ernst, Christoph M, Peschel, Andreas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8806190/ https://www.ncbi.nlm.nih.gov/pubmed/35044295 http://dx.doi.org/10.7554/eLife.66376 |
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