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Interleukin-18 promotes the antitumor ability of natural killer cells in colorectal cancer via the miR-574-3p/TGF-β1 axis

Interleukin (IL)-18 has a clear antitumor effect; however, its mechanisms of action are not understood in patients with colorectal cancer (CRC). Here, we investigated the potential mechanism of IL-18 in CRC. The results showed that IL-18 treatment alone had no effect on HCT116 cells apoptosis, where...

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Detalles Bibliográficos
Autores principales: Li, Yin-Peng, Du, Xian-Rong, Zhang, Ru, Yang, Qiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8806203/
https://www.ncbi.nlm.nih.gov/pubmed/33660570
http://dx.doi.org/10.1080/21655979.2021.1880717