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Fus knockdown inhibits the profibrogenic effect of cardiac fibroblasts induced by angiotensin II through targeting Pax3 thereby regulating TGF-β1/Smad pathway

The Angiotensin II/transforming growth factor-β1 (AngII/TGF-β1) signal axis is an important regulatory pathway for atrial fibrosis, which can contribute to atrial fibrillation (AF). Fused in sarcoma (FUS) was recently found to regulate cardiac diseases. This study aimed to investigate whether FUS co...

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Detalles Bibliográficos
Autores principales: Wang, Guoqiang, Wu, Hong, Liang, Peng, He, Xiaojiao, Liu, Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8806211/
https://www.ncbi.nlm.nih.gov/pubmed/33896391
http://dx.doi.org/10.1080/21655979.2021.1918522