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Combining bulk and single-cell RNA-sequencing data to reveal gene expression pattern of chondrocytes in the osteoarthritic knee

Osteoarthritis (OA) occurs mostly in the knees, hips, finger interphalangeal joints, and spinal facet joints, and is characterized by cartilage degeneration. The existing bulk RNA sequencing (bulk RNA-seq) and single-cell sequencing (scRNA-seq) data for chondrocytes in the osteoarthritic knee joint...

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Detalles Bibliográficos
Autores principales: Li, Xiaoyu, Liao, Zheting, Deng, Zhonghao, Chen, Nachun, Zhao, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8806218/
https://www.ncbi.nlm.nih.gov/pubmed/33749514
http://dx.doi.org/10.1080/21655979.2021.1903207