Ligustrazine induces viability, suppresses apoptosis and autophagy of retinal ganglion cells with ischemia/reperfusion injury through the PI3K/Akt/mTOR signaling pathway

Ligustrazine, an alkaloid monomer extracted from Chuanxiong Rhizoma, has the function of protecting nerve cells. However, the effect and mechanism of ligustrazine on retinal ischemia/reperfusion (I/R) injury still need to be clarified. In our study, retinal ganglion cells (RGC-5) were used to establ...

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Detalles Bibliográficos
Autores principales: Du, Hong-yan, Wang, Rong, Li, Jian-liang, Luo, Huang, Xie, Xiao-yan, Yan, Ran, Jian, Yue-ling, Cai, Jin-ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8806313/
https://www.ncbi.nlm.nih.gov/pubmed/33522374
http://dx.doi.org/10.1080/21655979.2021.1880060

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8806313/
https://www.ncbi.nlm.nih.gov/pubmed/33522374
http://dx.doi.org/10.1080/21655979.2021.1880060

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