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Crosstalk of low density lipoprotein and liposome as a paradigm for targeting of 5-fluorouracil into hepatic cells: cytotoxicity and liver deposition

This study aimed to utilize cholesterol conjugation of 5-fluorouracil (5-FUC) and liposomal formulas to enhance the partitioning of 5-FU into low density lipoprotein (LDL) to target hepatocellular carcinoma (HCC). Thus, 5-FU and 5-FUCwere loaded into liposomes. Later, the direct loading and transfer...

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Detalles Bibliográficos
Autores principales: Alanazi, Saleh A., Harisa, Gamaleldin I., Badran, Mohamed M., Alanazi, Fars K., Elzayat, Ehab, Alomrani, Abdullah H., Al Meanazel, Osaid T., Al Meanazel, Ahmed T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8806320/
https://www.ncbi.nlm.nih.gov/pubmed/33678142
http://dx.doi.org/10.1080/21655979.2021.1896202