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Crosstalk of low density lipoprotein and liposome as a paradigm for targeting of 5-fluorouracil into hepatic cells: cytotoxicity and liver deposition
This study aimed to utilize cholesterol conjugation of 5-fluorouracil (5-FUC) and liposomal formulas to enhance the partitioning of 5-FU into low density lipoprotein (LDL) to target hepatocellular carcinoma (HCC). Thus, 5-FU and 5-FUCwere loaded into liposomes. Later, the direct loading and transfer...
Autores principales: | Alanazi, Saleh A., Harisa, Gamaleldin I., Badran, Mohamed M., Alanazi, Fars K., Elzayat, Ehab, Alomrani, Abdullah H., Al Meanazel, Osaid T., Al Meanazel, Ahmed T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8806320/ https://www.ncbi.nlm.nih.gov/pubmed/33678142 http://dx.doi.org/10.1080/21655979.2021.1896202 |
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