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Fat mass and obesity-associated protein (FTO) mediates signal transducer and activator of transcription 3 (STAT3)-drived resistance of breast cancer to doxorubicin

Excessive activation of signal transducer and activator of transcription 3 (STAT3) is implicated in breast cancer (BC) chemoresistance, but its underlying mechanism is not fully understood. There are STAT3 binding sites in fat mass and obesity-associated protein (FTO) promoter region, thus STAT3 may...

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Detalles Bibliográficos
Autores principales: Wang, Yan, Cheng, Zhiqiang, Xu, Jing, Lai, Meina, Liu, Liming, Zuo, Min, Dang, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8806322/
https://www.ncbi.nlm.nih.gov/pubmed/34076564
http://dx.doi.org/10.1080/21655979.2021.1924544