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Fat mass and obesity-associated protein (FTO) mediates signal transducer and activator of transcription 3 (STAT3)-drived resistance of breast cancer to doxorubicin
Excessive activation of signal transducer and activator of transcription 3 (STAT3) is implicated in breast cancer (BC) chemoresistance, but its underlying mechanism is not fully understood. There are STAT3 binding sites in fat mass and obesity-associated protein (FTO) promoter region, thus STAT3 may...
Autores principales: | Wang, Yan, Cheng, Zhiqiang, Xu, Jing, Lai, Meina, Liu, Liming, Zuo, Min, Dang, Lin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8806322/ https://www.ncbi.nlm.nih.gov/pubmed/34076564 http://dx.doi.org/10.1080/21655979.2021.1924544 |
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