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AGEs/RAGE blockade downregulates Endothenin-1 (ET-1), mitigating Human Umbilical Vein Endothelial Cells (HUVEC) injury in deep vein thrombosis (DVT)

This study is aimed at identifying the roles of AGE/RAGE and ET-1 in deep vein thrombosis (DVT). Advanced glycation end products (AGEs) in glycated human serum albumin (M-HSA) were detected by ELISA. The viability of HUVECs was examined by CCK-8 assay. Flow cytometry was performed to detect cell apo...

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Detalles Bibliográficos
Autores principales: Zhang, Yunxin, Liu, Jianlong, Jia, Wei, Tian, Xuan, Jiang, Peng, Cheng, Zhiyuan, Li, Jinyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8806329/
https://www.ncbi.nlm.nih.gov/pubmed/33896376
http://dx.doi.org/10.1080/21655979.2021.1917980