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Tetrandrine may treat membranous glomerulopathy via P13K/Akt signaling pathway regulation: therapeutic mechanism validation using Heymann nephritis rat model

Membranous glomerulopathy (MGN) is an autoimmune kidney disease that is the primary cause of nephrotic syndrome (NS) in adults. Tetrandrine, a bisbenzylisoquinoline alkaloid, is known to have numerous pharmacological effects. In this study, network pharmacology analysis and experimental validation w...

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Detalles Bibliográficos
Autores principales: Yin, Jiazhen, Lin, Jiazhen, Yu, Jin, Wei, Xia, Zhu, Bin, Zhu, Caifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8806448/
https://www.ncbi.nlm.nih.gov/pubmed/34463195
http://dx.doi.org/10.1080/21655979.2021.1973862