Plumbagin attenuates traumatic tracheal stenosis in rats and inhibits lung fibroblast proliferation and differentiation via TGF-β1/Smad and Akt/mTOR pathways

Traumatic tracheal stenosis (TS) is a serious respiratory disease characterized by hyperplasia of airway granulation. Plumbagin (PLB) is a natural naphthoquinone component with anti-fibrotic properties. This research aimed to explore the roles of PLB in alleviating TS and the underlying mechanisms....

Descripción completa

Detalles Bibliográficos
Autores principales: Shi, Wei, Fang, Yuanyuan, Jiang, Yueming, Jiang, Siyang, Li, Yu, Li, Wentao, Xu, Mingpeng, Aschner, Michael, Liu, Guangnan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8806467/
https://www.ncbi.nlm.nih.gov/pubmed/34304701
http://dx.doi.org/10.1080/21655979.2021.1954580

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8806467/
https://www.ncbi.nlm.nih.gov/pubmed/34304701
http://dx.doi.org/10.1080/21655979.2021.1954580

Ejemplares similares