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Plumbagin attenuates traumatic tracheal stenosis in rats and inhibits lung fibroblast proliferation and differentiation via TGF-β1/Smad and Akt/mTOR pathways

Traumatic tracheal stenosis (TS) is a serious respiratory disease characterized by hyperplasia of airway granulation. Plumbagin (PLB) is a natural naphthoquinone component with anti-fibrotic properties. This research aimed to explore the roles of PLB in alleviating TS and the underlying mechanisms....

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Detalles Bibliográficos
Autores principales:	Shi, Wei, Fang, Yuanyuan, Jiang, Yueming, Jiang, Siyang, Li, Yu, Li, Wentao, Xu, Mingpeng, Aschner, Michael, Liu, Guangnan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2021
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8806467/ https://www.ncbi.nlm.nih.gov/pubmed/34304701 http://dx.doi.org/10.1080/21655979.2021.1954580

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