Rosmarinic acid inhibits proliferation and migration, promotes apoptosis and enhances cisplatin sensitivity of melanoma cells through inhibiting ADAM17/EGFR/AKT/GSK3β axis

Rosmarinic acid (RA), a naturally occurring polyphenolic compound, exerts multiple biological properties including anti-cancer. The metalloprotease, a disintegrin and metalloproteinase 17 (ADAM17), can activate ligands of the epidermal growth factor receptor (EGFR) and contribute to tumor progressio...

Descripción completa

Detalles Bibliográficos
Autores principales: Huang, Lin, Chen, Jiangyan, Quan, Jin, Xiang, Debing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8806498/
https://www.ncbi.nlm.nih.gov/pubmed/34224305
http://dx.doi.org/10.1080/21655979.2021.1941699

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8806498/
https://www.ncbi.nlm.nih.gov/pubmed/34224305
http://dx.doi.org/10.1080/21655979.2021.1941699

Ejemplares similares