Lemur tyrosine kinase-3 (LMTK3) induces chemoresistance to cetuximab in colorectal cancer via the ERK/MAPK pathway

As an oncogenic kinase in multiple cancers, LMTK3 was deeply implicated in cancer pathogenesis. Nevertheless, its biological function in colorectal cancer (CRC) is still unclear. In this study, LMTK3 mRNA expression was assessed by RT-qPCR. LMTK3, phospho-ERK1/2 (p-ERK1/2), ERK1/2, and cleaved caspa...

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Detalles Bibliográficos
Autores principales: Wang, Cheng, Yang, Miaomiao, Gu, Xi, Gu, Yanjing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8806509/
https://www.ncbi.nlm.nih.gov/pubmed/34516351
http://dx.doi.org/10.1080/21655979.2021.1974655

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8806509/
https://www.ncbi.nlm.nih.gov/pubmed/34516351
http://dx.doi.org/10.1080/21655979.2021.1974655

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