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High-altitude hypoxia exacerbates dextran sulfate sodium (DSS)-induced colitis by upregulating Th1 and Th17 lymphocytes

High altitude hypoxia (HAH) involves the pathogenesis of ulcerative colitis (UC) and gastrointestinal erosions. However, the mechanism of effects of HAH in colitis remains controversial. This study reports the immunomodulation mediated by HAH to enhancing the severity of UC in the mice model. BALB/c...

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Detalles Bibliográficos
Autores principales: Gamah, Mohammed, Alahdal, Murad, Zhang, Yu, Zhou, Yiling, Ji, Qiaorong, Yuan, Zhouyang, Han, Ying, Shen, Xiangqun, Ren, Yanming, Zhang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8806510/
https://www.ncbi.nlm.nih.gov/pubmed/34666625
http://dx.doi.org/10.1080/21655979.2021.1975017