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Exosomal-mediated transfer of APCDD1L-AS1 induces 5-fluorouracil resistance in oral squamous cell carcinoma via miR-1224-5p/nuclear receptor binding SET domain protein 2 (NSD2) axis

Oral squamous cell carcinoma (OSCC) poses a threat to public health worldwide. LncRNA APCDD1L-AS1 has been reported to participate in tumorigenesis and development of acquired chemoresistance. However, the role of APCDD1L-AS1 in 5-fluorouracil (5-FU) resistance regulation within OSCC is still obscur...

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Detalles Bibliográficos
Autores principales: Li, Shen, Shi, Zhiyan, Fu, Suwei, Li, Qingfu, Li, Bei, Sang, Lixiao, Wu, Donghong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8806529/
https://www.ncbi.nlm.nih.gov/pubmed/34546854
http://dx.doi.org/10.1080/21655979.2021.1979442