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Overexpression of PLK1 relieved the myocardial ischemia-reperfusion injury of rats through inducing the mitophagy and regulating the p-AMPK/FUNDC1 axis

Myocardial cell injury caused by myocardial ischemia and reperfusion is one of the main causes of the occurrence and development of heart disease. Recent study has shown that inducing mitophagy of cardiomyocytes is a crucial method to alleviate ischemia-reperfusion injury. While, Polo-like kinase 1...

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Detalles Bibliográficos
Autores principales: Mao, Shan, Tian, Shuning, Luo, Xianghong, Zhou, Ming, Cao, Zheng, Li, Ji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8806532/
https://www.ncbi.nlm.nih.gov/pubmed/34115550
http://dx.doi.org/10.1080/21655979.2021.1938500