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Cullin3 aggravates the inflammatory response of periodontal ligament stem cells via regulation of SHH signaling and Nrf2

It is found that the activation of Sonic Hedgehog (SHH) signaling pathway is related to the degree of inflammation in patients suffering from periodontitis. Cullin3 (CUL3), an important ubiquitin ligase, can control SHH signaling. In this study, we were dedicated to clarify the roles of SHH and CUL3...

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Detalles Bibliográficos
Autores principales: Chen, Wanhong, Su, Jiangling, Cai, Shixiong, Shi, Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8806625/
https://www.ncbi.nlm.nih.gov/pubmed/34193016
http://dx.doi.org/10.1080/21655979.2021.1943603