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Overexpression of Notch2 enhances radiosensitivity via inhibition of the AKT/mTOR signaling pathway in nasopharyngeal carcinoma

Our previous study found that in nasopharyngeal carcinoma (NPC) cells, overexpression of Notch2 can inhibit epithelial-mesenchymal transition (EMT), which plays a vital role in mediating radiosensitivity. The purpose of this study was to explore the radiosensitizing efficacy of the Notch2 gene in NP...

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Detalles Bibliográficos
Autores principales: Wu, Li-Zhi, Huang, Mao-Ling, Qi, Cheng-Lin, Shen, Li-Jun, Zou, You, Yang, Rui, Sheng, Jian-Fei, Chen, Shi-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8806669/
https://www.ncbi.nlm.nih.gov/pubmed/34224316
http://dx.doi.org/10.1080/21655979.2021.1949236