G protein-coupled receptor 39 activation alleviates oxidized low-density lipoprotein-induced macrophage inflammatory response, lipid accumulation and apoptosis by inducing A20 expression

G protein-coupled receptor 39 (GPR39) agonist weakens oxidized low-density lipoprotein (ox-LDL)-induced attachment of monocytes to vascular endothelial cells and thus alleviates atherosclerosis. This study looks at whether GPR39 protects macrophages against ox-LDL-induced inflammation and apoptosis...

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Detalles Bibliográficos
Autores principales: Chen, Lu, Fang, Zhengdong, Wang, Xiaotian, Sun, Xiaojie, Ge, Xinbao, Cheng, Can, Hu, Hejie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8806696/
https://www.ncbi.nlm.nih.gov/pubmed/34288802
http://dx.doi.org/10.1080/21655979.2021.1952917

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8806696/
https://www.ncbi.nlm.nih.gov/pubmed/34288802
http://dx.doi.org/10.1080/21655979.2021.1952917

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