Ibrutinib ameliorates cerebral ischemia/reperfusion injury through autophagy activation and PI3K/Akt/mTOR signaling pathway in diabetic mice

Bruton’s tyrosine kinase (BTK) is involved in the diabetogenic process and cerebral ischemic injury. However, it remained unclear whether BTK inhibition has remedial effects on ischemia/reperfusion (I/R) injury complicated with diabetes. We aim to investigate the regulatory role and potential mechan...

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Detalles Bibliográficos
Autores principales: Jin, Lei, Mo, Yun, Yue, Er-Li, Liu, Yuan, Liu, Kang-Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8806753/
https://www.ncbi.nlm.nih.gov/pubmed/34605340
http://dx.doi.org/10.1080/21655979.2021.1974810

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8806753/
https://www.ncbi.nlm.nih.gov/pubmed/34605340
http://dx.doi.org/10.1080/21655979.2021.1974810

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