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Formononetin protects against ox-LDL-induced endothelial dysfunction by activating PPAR-γ signaling based on network pharmacology and experimental validation

Formononetin (FMNT), a flavonoid identified from the Chinese herb Astragalus membranaceus, possesses anti-inflammatory or anti-oxidative properties in different human diseases. This study aims to comprehensively elucidate the function of FMNT in atherosclerosis and its underlying mechanisms. Online...

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Detalles Bibliográficos
Autores principales: Zhang, Baohua, Hao, Zhongwei, Zhou, Wenli, Zhang, Shan, Sun, Mingyan, Li, Honglei, Hou, Naijing, Jing, Cui, Zhao, Mingxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8806800/
https://www.ncbi.nlm.nih.gov/pubmed/34369277
http://dx.doi.org/10.1080/21655979.2021.1959493