Montelukast attenuates interleukin IL-1β-induced oxidative stress and apoptosis in chondrocytes by inhibiting CYSLTR1 (Cysteinyl Leukotriene Receptor 1) and activating KLF2 (Kruppel Like Factor 2)

Montelukast is a cysteinyl leukotriene receptor 1 (CysLTR1) antagonist widely used to suppress the inflammatory response in asthma and allergic rhinitis. This study aimed to investigate the potential impacts of montelukast on osteoarthritis (OA) progression. To determine the role of montelukast in O...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Zongwei, Wang, Jianming, Ma, Yumin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8806840/
https://www.ncbi.nlm.nih.gov/pubmed/34565285
http://dx.doi.org/10.1080/21655979.2021.1984003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8806840/
https://www.ncbi.nlm.nih.gov/pubmed/34565285
http://dx.doi.org/10.1080/21655979.2021.1984003

Ejemplares similares