Pyrroloquinoline quinone (PQQ) alleviated sepsis-induced acute liver injury, inflammation, oxidative stress and cell apoptosis by downregulating CUL3 expression

PQQ has anti-inflammatory and anti-oxidant effects. PQQ can relieve high glucose-induced renal cell damage by suppressing Keap1 expression. Keap1 can interact with CUL3. Upregulation of CUL3 facilitates the apoptosis of LPS-induced podocytes. Based on knowledge above, this current work was designed...

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Detalles Bibliográficos
Autores principales: Wu, Yanhong, Zhao, Meiling, Lin, Zhaoheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8806920/
https://www.ncbi.nlm.nih.gov/pubmed/34227919
http://dx.doi.org/10.1080/21655979.2021.1935136

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8806920/
https://www.ncbi.nlm.nih.gov/pubmed/34227919
http://dx.doi.org/10.1080/21655979.2021.1935136

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