Tranilast inhibits angiotensin II-induced myocardial fibrosis through S100A11/ transforming growth factor-β (TGF-β1)/Smad axis

Tranilast has an ameliorative effect on myocardial fibrosis (MF), but the specific mechanism has not been studied. S100A11 is a key regulator of collagen expression in MF. In this paper, we will study the regulatory roles of Tranilast and S100A11 in MF. After the introduction of angiotensin II (AngI...

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Detalles Bibliográficos
Autores principales: Chen, Youquan, Huang, Ming, Yan, Yi, He, Dequan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8806955/
https://www.ncbi.nlm.nih.gov/pubmed/34663163
http://dx.doi.org/10.1080/21655979.2021.1982322

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8806955/
https://www.ncbi.nlm.nih.gov/pubmed/34663163
http://dx.doi.org/10.1080/21655979.2021.1982322

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