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Comparative analysis of circRNA expression profile and circRNA-miRNA-mRNA regulatory network between palmitic and stearic acid-induced lipotoxicity to pancreatic β cells

Chronic exposure to high concentrations of circulating palmitic acid and stearic acid leads to impaired β cell function, which accelerates the development of type 2 diabetes. However, differences in the mechanisms underlying this process between these two saturated fatty acids remain largely unknown...

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Detalles Bibliográficos
Autores principales: Zhang, Yunjin, Zhao, Qingrui, Su, Shenghan, Dan, Lingfeng, Li, Xuebei, Wang, Yu, Lin, Yuqing, Tian, Zhen, Sun, Changhao, Lu, Huimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8806959/
https://www.ncbi.nlm.nih.gov/pubmed/34654356
http://dx.doi.org/10.1080/21655979.2021.1992333